Peptides have been a skincare buzzword for the past few years, but more recently, neuropeptides have garnered lots of attention in the world of peptide skincare. The skin contains natural peptides, which contribute to the structural strength of the skin to keep it plump, firm and youthful. Luckily, skincare science has figured out how to create peptides in the lab to signal to the skin that it needs to make more collagen. These strands of amino acids penetrate the skin to address common skincare concerns, including wrinkles, from the inside out.

Because of their effectiveness, peptides and the products containing them tend to be expensive. Look for signal peptides like Matrixyl or copper peptides (which promote collagen production and act as antioxidants) in skincare ingredient lists.

As for neuropeptides, proponents claim they act by affecting neurotransmitters in the skin. When this happens, nerve cells in the skin supposedly cease communicating and relax, resulting in smoother and less wrinkled skin. Some neuropeptide skincare products even claim to work as well as Botox to relax wrinkles and keep new ones from forming. Dr. Perricone’s line heavily features neuropeptides, at a hefty price.

While signal peptides and copper peptides have both scientific and anecdotal evidence for how they improve skin, I don’t recommend neuropeptides until more efficacy studies have been done on them.

Skincare lines with peptides include:

  • Oil of Olay Regenerist
  • Strivectin
  • Dr. Dennis Gross
  • Mario Badescu